Persistent adrenarche syndrome

Persistent adrenarche syndrome
Synonyms
Pronounce	N/A
Specialty	Endocrinology
Symptoms	Early development of pubic hair, axillary hair, body odor, and acne
Complications	N/A
Onset	Typically between ages 6-8 in girls, 7-9 in boys
Duration	Chronic
Types	N/A
Causes	Increased production of adrenal androgens
Risks
Diagnosis	Clinical evaluation, measurement of DHEA-S levels
Differential diagnosis	Precocious puberty, congenital adrenal hyperplasia
Prevention	N/A
Treatment	Monitoring, reassurance, addressing symptoms if necessary
Medication	N/A
Prognosis	N/A
Frequency	Relatively common
Deaths	N/A

Persistent adrenarche syndrome (PAS) is a medical condition characterized by the premature development of secondary sexual characteristics. This condition is caused by the early activation of the adrenal glands, which produce hormones responsible for the development of these characteristics.

Symptoms

The symptoms of PAS can vary, but often include the early development of pubic hair, body odor, and acne. In some cases, individuals with PAS may also experience rapid growth and advanced bone age.

Causes

The exact cause of PAS is unknown, but it is believed to be related to an overactive adrenal gland. The adrenal gland is responsible for producing hormones that regulate a variety of bodily functions, including the development of secondary sexual characteristics. In individuals with PAS, the adrenal gland begins producing these hormones at an earlier age than normal.

Diagnosis

Diagnosis of PAS is typically made through a combination of physical examination and laboratory tests. The physical examination may reveal signs of premature adrenarche, such as the early development of pubic hair or body odor. Laboratory tests can be used to measure the levels of adrenal hormones in the body.

Treatment

Treatment for PAS typically involves managing the symptoms of the condition. This can include the use of medications to control the production of adrenal hormones. In some cases, surgery may be necessary to remove the overactive adrenal gland.

See also

• Adrenal gland
• Hormone
• Puberty
• Adrenarche

References

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