Central lobule
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Central lobule is a term used in anatomy to refer to a specific part of the cerebellum, which is a region of the brain that plays an important role in motor control. The central lobule is also known as the culmen and is part of the anterior lobe of the cerebellum.
Etymology
The term "central lobule" is derived from the Latin word "lobulus", which means "a small lobe". The prefix "central" refers to its location in the center of the anterior lobe of the cerebellum.
Anatomy
The central lobule is located in the anterior lobe of the cerebellum, which is the front part of the cerebellum. It is bordered by the primary fissure anteriorly and the preclival fissure posteriorly. The central lobule is part of the vermis, which is a worm-like structure in the middle of the cerebellum that connects the two cerebellar hemispheres.
Function
The central lobule, like the rest of the cerebellum, is involved in the coordination of voluntary motor movements, balance, and equilibrium, and muscle tone. It receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine-tune motor activity.
Clinical significance
Damage to the central lobule can result in a variety of neurological disorders, including ataxia, which is characterized by a lack of voluntary coordination of muscle movements, and dysmetria, which is a lack of ability to judge distance or range of movement.
See also
References
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Contributors: Prab R. Tumpati, MD