Renal cortex
(Redirected from Cortical substance)
Renal Cortex
The renal cortex is the outer portion of the kidney. It contains the glomeruli and the renal tubules except for their parts in the medulla. Blood filtration, which is the first step in urine creation, occurs in the cortex. The renal cortex is surrounded on its outer edges by the renal capsule, a layer of fatty tissue that helps protect the kidney from damage.
Structure
The renal cortex is the part of the kidney where ultrafiltration occurs. It contains the glomeruli and the renal tubules, except for the loop of Henle which dips into the medullary area. The renal cortex is granular due to the presence of nephrons, the functional units of the kidney.
Function
The renal cortex plays a crucial role in the function of the kidney. It is involved in the production of urine, helping to filter out waste products from the blood. The filtration process begins in the glomerulus, a network of tiny blood vessels located in the cortex. The filtered blood then moves into the renal tubules, where further processing occurs.
Clinical significance
Damage to the renal cortex can lead to a number of health problems, including chronic kidney disease and renal failure. Conditions such as glomerulonephritis, which involves inflammation of the glomeruli, and pyelonephritis, a type of urinary tract infection that has reached the kidney, can also affect the renal cortex.
See also
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Contributors: Prab R. Tumpati, MD