Fibril
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Fibril is a term used in biology and medicine to describe a small or slender fiber. It is often used to refer to certain structures in the body, such as muscle fibrils and collagen fibrils.
Definition
A fibril is a long, slender, thread-like structure that is found in various parts of the body. It is typically composed of proteins and can be found in various tissues, including muscle and connective tissue. Fibrils can be seen under a microscope and are often involved in the structure and function of the tissues in which they are found.
Types of Fibrils
There are several types of fibrils, including:
- Muscle Fibrils: These are found in muscle tissue and are involved in muscle contraction. They are composed of proteins called actin and myosin.
- Collagen Fibrils: These are found in connective tissue and are involved in providing strength and flexibility to the tissue. They are composed of collagen, a protein that is abundant in the body.
- Amyloid Fibrils: These are abnormal fibrils that can accumulate in various tissues in the body. They are associated with a number of diseases, including Alzheimer's disease and Parkinson's disease.
Role in Disease
Fibrils play a role in a number of diseases. For example, in diseases such as Alzheimer's and Parkinson's, abnormal amyloid fibrils can accumulate in the brain and contribute to the disease process. In other diseases, such as certain types of arthritis, abnormal collagen fibrils can contribute to joint damage.
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Contributors: Prab R. Tumpati, MD