File:3D-SIM-1 NPC Confocal vs 3D-SIM.jpg

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Summary[edit]

Summary
Description Comparison of resolution obtained by confocal laser scanning microscopy (clsm, left) and 3D structured illumination microscopy (3D-SIM-Microscopy, right). Top images each show a nucleus of a mouse cell, the white boxes are magnified at the bottom. Nuclear pores (anti-NPC, red) nuclear envelope (anti-Lamin, green). Chromatin/DNA (DAPI, blue). scale bars: top 5 µm, bottom 1µm. For further information see: Schermelleh L, Carlton PM, Haase S, Shao L, Winoto L, Kner P, Burke B, Cardoso MC, Agard DA, Gustafsson MG, Leonhardt H, Sedat JW (June 2008). "Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy". Science (journal) 320 (5881): 1332–6. DOI:10.1126/science.1156947. PMID 18535242.
Source Wikimedia Commons file page
Author Lothar Schermelleh
Permission See original Commons license details.

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