File:Congenital eye diseases associated with neural crest defects in the anterior segment.jpg
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Summary
| Description | Figure 4. Congenital eye diseases associated with neural crest defects in the anterior segment. (A) Axenfeld-Rieger syndrome is characterized by anteriorization of Schwalbe’s line (posterior embryotoxon, black arrowheads) and iris hypoplasia, causing corectopia and pseudopolycoria (white arrows). Over half of affected individuals develop glaucoma, and many require placement of a glaucoma drainage device (asterisk) to control intraocular pressure. (B) Primary congenital glaucoma is due to developmental abnormalities in the trabecular meshwork and aqueous outflow tracts. As a result, elevated intraocular pressures in infants cause corneal edema and buphthalmos (increased eye size). (C) Peters anomaly shows central corneal opacification (black arrows) reflecting the abnormal separation of the lens vesicle from the surface ectoderm. |
| Date | |
| Source | https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2020.595896/full Williams AL and Bohnsack BL (2020) The Ocular Neural Crest: Specification, Migration, and Then What? Front. Cell Dev. Biol. 8:595896. doi: 10.3389/fcell.2020.595896 |
| Author | Williams AL and Bohnsack BL |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 19:21, 13 September 2024 | | 1,825 × 605 (162 KB) | Rasbak | {{Information |description=Figure 4. Congenital eye diseases associated with neural crest defects in the anterior segment. (A) Axenfeld-Rieger syndrome is characterized by anteriorization of Schwalbe’s line (posterior embryotoxon, black arrowheads) and iris hypoplasia, causing corectopia and pseudopolycoria (white arrows). Over half of affected individuals develop glaucoma, and many require placement of a glaucoma drainage device (asterisk) to control intraocular pressure. (B) Primary congeni... |
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