File:Eritroblastosis fetalis ku.png

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Summary[edit]

Summary
Description When an Rh− mother has an Rh+ fetus, fetal erythrocytes are introduced into the mother’s circulatory system before or during birth, leading to production of anti-Rh IgG antibodies. These antibodies remain in the mother and, if she becomes pregnant with a second Rh+ baby, they can cross the placenta and attach to fetal Rh+ erythrocytes. Complement-mediated hemolysis of fetal erythrocytes results in a lack of sufficient cells for proper oxygenation of the fetus. HDN can be prevented by administering Rho(D) immune globulin during and after each pregnancy with an Rh+ fetus. The immune globulin binds fetal Rh+ RBCs that gain access to the mother’s bloodstream, preventing activation of her primary immune response.
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Author https://openstax.org
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current13:37, 8 June 2026Thumbnail for version as of 13:37, 8 June 2026961 × 520 (298 KB)Maintenance script (talk | contribs)== Summary == Importing file

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