File:Paracetamol metabolism.svg

From WikiMD's medical encyclopedia

Original file ‎(SVG file, nominally 385 × 385 pixels, file size: 185 KB)

This file is from Wikimedia Commons and may be used by other projects. The description on its file description page there is shown below.

Summary

Description
English: Simplified schematic of the key pathways of paracetamol metabolism in the human body. The first step in conversion of paracetamol to NAPQI has been omitted for clarity.
Set in Myriad Pro.
Legend
 
Pathways to non-toxic metabolites
 
Pathway to toxic metabolites (CYP-mediated)
 
Detoxification pathway
Abbreviations
GlcA, glucuronic acid; GSH, glutathione; NAPQI, N-acetyl-p-benzoquinone imine.
Português: Esquema simplificado das principais vias de biotransformação do paracetamol em humanos. Para maior clareza, omitiu-se a primeira etapa da conversão do paracetamol à N-acetil-benzoquinoneimina.
Diagrama composto em Myriad Pro.
Legenda
 
Vias de conversão a metabólitos atóxicos
 
Via de conversão a metabólitos tóxicos (mediada pelo sistema P450)
 
Via de detoxificação
Abreviações
GlcA, ácido glicurônico; GSH, glutationa; NAPQI, N-acetil-benzoquinoneimina.
Date
Source Own work based on: Henry, John (1995) "Poisoning" in Marshall, William Leonard, ed. Clinical biochemistry: metabolic and clinical aspects, Edinburgh: Churchill Livingstone, pp. 666 Retrieved on 18 January 2009. ISBN: 9780443043413. and Hendrickson, Robert G.; Bizovi, Kenneth E. (2006) "Acetaminophen" in Goldfrank's toxicologic emergencies, New York City: McGraw-Hill, pp. 525 Retrieved on 18 January 2009. ISBN: 9780071437639.
Author Fvasconcellos
Other versions Derivative works of this file:
SVG development
InfoField
 The SVG code is valid.
 This diagram was created with Inkscape.

Licensing

Public domain This image of a simple structural formula is ineligible for copyright and therefore in the public domain, because it consists entirely of information that is common property and contains no original authorship.
Public domain This work has been released into the public domain by its author, Fvasconcellos. This applies worldwide.
In some countries this may not be legally possible; if so:
Fvasconcellos grants anyone the right to use this work for any purpose, without any conditions, unless such conditions are required by law.

Captions

metabolic pathway of paracetamol

Items portrayed in this file

depicts

inception

18 January 2009

data size

189,231 byte

media type

image/svg+xml

checksum

fefae28e3ce0eea036cfe6ad4ffce01339e218db

determination method or standard: SHA-1

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current13:13, 19 January 2009Thumbnail for version as of 13:13, 19 January 2009385 × 385 (185 KB)Fvasconcellosfixed NAPQI structure

The following page uses this file:

Metadata

This file contains additional information, probably added from the digital camera or scanner used to create or digitize it.

If the file has been modified from its original state, some details may not fully reflect the modified file.

Retrieved from "https://wikimd.org/wiki/File:Paracetamol_metabolism.svg"