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Summary
DescriptionRNAi-simplified.png
English: Overview of RNA interference. The dicer enzymes produce siRNA from double-stranded RNA and mature miRNA from precursor miRNA. miRNA or siRNA is bound to an argonaute enzyme and an effector complex is formed, either a RISC (RNA-induced silencing complex) or RITS (RNA-induced transcriptional silencing) complex. RITS affects the rate of transcription by histone and DNA methylation, whereas RISC degrades mRNA to prevent it from being translated.
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This figure is adapted from one by Matzke MA, Matzke AJM (2004) Planting the Seeds of a New Paradigm. PLoS Biol 2(5): e133 doi:10.1371/journal.pbio.0020133.
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This figure is adapted from one by Matzke MA, Matzke AJM
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File:RNAi-simplified.svg is a vector version of this file. It should be used in place of this PNG file when not inferior.
2007-12-21 10:17 Narayanese 800×684× (118099 bytes) Overview of RNA interference. This figure is adapted from one by Matzke MA, Matzke AJM (2004) Planting the Seeds of a New Paradigm. PLoS Biol 2(5): e133 [http://dx.doi.org/10.1371/journal.pbio.0020133].
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