Increlex
Increlex
Increlex (pronounced in-kre-lex) is a brand name for the drug mecasermin, a synthetic version of insulin-like growth factor 1 (IGF-1). It is used to treat growth failure in children with severe primary IGF-1 deficiency or with growth hormone (GH) gene deletion who have developed neutralizing antibodies to growth hormone.
Etymology
The name "Increlex" is derived from the words "increase" and "flex", referring to its function of increasing growth in children.
Usage
Increlex is used when the body does not produce enough natural IGF-1. It works by helping the body grow and develop, especially when the body cannot produce enough of its own growth hormone. It is not used instead of growth hormone, but as a supplement to it.
Side Effects
Common side effects of Increlex include hypoglycemia, injection site reactions, allergic reactions, and enlarged tonsils. Serious side effects may include hypoglycemia, lipodystrophy, and intracranial hypertension.
Related Terms
- Mecasermin: The generic name for Increlex.
- Insulin-like growth factor 1 (IGF-1): A hormone that along with growth hormone (GH) helps promote normal bone and tissue growth and development.
- Growth hormone (GH): A hormone that helps regulate body composition, body fluids, muscle and bone growth, sugar and fat metabolism, and possibly heart function.
External links
- Medical encyclopedia article on Increlex
- Wikipedia's article - Increlex
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