Keratolytic agents
Keratolytic Agents
Keratolytic agents (pronunciation: ker-uh-toh-LIT-ik) are a type of medication used in dermatology to treat various skin conditions. They work by softening and breaking down the outermost layer of the skin, known as the stratum corneum, which helps to shed skin cells more easily.
Etymology
The term "keratolytic" is derived from the Greek words "keras," meaning horn, and "lysis," meaning loosening or breaking down. This refers to the agent's ability to break down the keratin, a type of protein that makes up the outer layer of the skin.
Usage
Keratolytic agents are used to treat a variety of skin conditions, including psoriasis, eczema, corns, calluses, and warts. They can also be used to treat acne by helping to unblock pores and reduce inflammation.
Types of Keratolytic Agents
There are several types of keratolytic agents, including:
- Salicylic Acid: This is one of the most commonly used keratolytic agents. It works by dissolving the intercellular cement substance that holds skin cells together, allowing them to be shed more easily.
- Urea: This agent is used to treat dry and rough skin conditions. It works by breaking down the dead skin cells and increasing water content in the skin.
- Sulfur: This agent has been used for centuries to treat various skin conditions. It works by slowing down the growth of skin cells and killing bacteria that can cause acne.
- Retinoids: These are derived from vitamin A and are used to treat acne and other skin conditions. They work by promoting the turnover of skin cells and reducing inflammation.
Side Effects
Like all medications, keratolytic agents can have side effects. These can include skin irritation, redness, and peeling. It's important to use these medications as directed by a healthcare provider to minimize the risk of side effects.
External links
- Medical encyclopedia article on Keratolytic agents
- Wikipedia's article - Keratolytic agents
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