Muromonab
Muromonab
Muromonab (pronunciation: myoo-roe-MOE-nab) is a type of monoclonal antibody used in the treatment of transplant rejection. It is also known by its trade name, Orthoclone OKT3.
Etymology
The name "Muromonab" is derived from its composition: Murine (mouse) monoclonal antibody. It is a mouse antibody produced in the laboratory, designed to target and bind to a specific protein found on the surface of human T cells.
Usage
Muromonab is used to prevent or treat acute rejection in patients who have received a kidney transplant. It works by suppressing the body's immune response, preventing it from attacking the transplanted organ.
Related Terms
- Monoclonal antibody: A type of protein made in the laboratory that can bind to substances in the body, including cancer cells.
- Transplant rejection: A process in which a transplant recipient's immune system attacks the transplanted organ or tissue.
- Kidney transplant: A surgical procedure to place a healthy kidney from a live or deceased donor into a person whose kidneys no longer function properly.
Side Effects
Like all medications, Muromonab can cause side effects. These may include flu-like symptoms, such as fever and chills, as well as more serious effects like difficulty breathing and chest pain. Patients should report any side effects to their healthcare provider.
See Also
- Immunosuppressive drug: A type of drug that lowers the body's ability to reject a transplanted organ.
- T cell: A type of white blood cell that is of key importance to the immune system and is at the core of adaptive immunity, the system that tailors the body's immune response to specific pathogens.
External links
- Medical encyclopedia article on Muromonab
- Wikipedia's article - Muromonab
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