Clear cell acanthoma
Clear cell acanthoma (pronunciation: kleer sel ak-an-tho-ma) is a benign dermatological condition characterized by a solitary, well-circumscribed, shiny, red-brown nodule or plaque. It was first described by Degos et al. in 1962. The term "clear cell" refers to the appearance of the cells under a microscope, while "acanthoma" is derived from the Greek words "akantha" meaning thorn and "oma" meaning tumor, indicating a thorny or spiky tumor.
Etymology
The term "Clear cell acanthoma" is derived from the Greek words "akantha" meaning thorn and "oma" meaning tumor, indicating a thorny or spiky tumor. The "clear cell" part of the name refers to the appearance of the cells under a microscope.
Clinical Presentation
Clear cell acanthoma typically presents as a solitary, well-circumscribed, shiny, red-brown nodule or plaque. It is most commonly found on the lower extremities, particularly the legs. The lesion may be asymptomatic or may cause mild itching.
Diagnosis
The diagnosis of clear cell acanthoma is typically made based on the clinical presentation and confirmed with a skin biopsy. Under the microscope, the lesion is characterized by clear cells in the epidermis, which is the outermost layer of the skin.
Treatment
Treatment for clear cell acanthoma typically involves surgical removal of the lesion. Other treatment options may include cryotherapy, which involves freezing the lesion with liquid nitrogen, or laser therapy.
Related Terms
- Dermatology: The branch of medicine dealing with the skin and its diseases.
- Skin Biopsy: A procedure in which a sample of skin tissue is removed and examined under a microscope.
- Cryotherapy: A treatment that uses extreme cold produced by liquid nitrogen or argon gas to destroy abnormal tissue.
External links
- Medical encyclopedia article on Clear cell acanthoma
- Wikipedia's article - Clear cell acanthoma
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