Tubocurarine
Tubocurarine
Tubocurarine (pronounced: too-boh-kyoo-RAH-reen) is a type of non-depolarizing neuromuscular-blocking drug that is derived from the plant Chondrodendron tomentosum. It is historically significant as the first muscle relaxant to be used in anesthesia.
Etymology
The term "tubocurarine" is derived from the plant species Tubocurare, an alternative name for Chondrodendron tomentosum, from which the drug is extracted. The suffix "-ine" is commonly used in the names of alkaloids.
Pharmacology
Tubocurarine works by blocking the action of acetylcholine, a neurotransmitter that transmits signals in the nervous system. By doing so, it prevents muscle contraction, leading to muscle relaxation and paralysis. This makes it useful in surgical procedures where muscle relaxation is required.
Clinical Use
Tubocurarine is primarily used in the field of anesthesiology to induce muscle relaxation during surgery. It is also used in intensive care units to facilitate mechanical ventilation. However, its use has declined in recent years due to the development of newer, safer neuromuscular-blocking drugs.
Related Terms
See Also
External links
- Medical encyclopedia article on Tubocurarine
- Wikipedia's article - Tubocurarine
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski