8,9-Dehydroestrone
8,9-Dehydroestrone (pronunciation: 8,9-de-hydro-es-trone) is a steroid and a metabolite of estrone. It is also known as 8,9-unsaturated estrone.
Etymology
The term "8,9-Dehydroestrone" is derived from the Greek words "de" meaning "without", "hydro" meaning "water", and "estrone" referring to the parent compound. The "8,9" refers to the positions of the carbon atoms in the steroid structure where the dehydrogenation (removal of hydrogen) occurs.
Chemistry
8,9-Dehydroestrone is a steroid, a type of organic compound with four rings arranged in a specific configuration. It is a metabolite of estrone, meaning it is a product of the metabolism of estrone. The "8,9" in its name refers to the positions of the carbon atoms in the steroid structure where the dehydrogenation (removal of hydrogen) occurs, resulting in a double bond between these two carbon atoms.
Biological Role
In the human body, 8,9-Dehydroestrone is produced from estrone through the action of the enzyme 17β-Hydroxysteroid dehydrogenase. It is less potent than estrone and other estrogens, but still has some estrogenic activity.
Related Terms
See Also
External links
- Medical encyclopedia article on 8,9-Dehydroestrone
- Wikipedia's article - 8,9-Dehydroestrone
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