Active chromatin sequence
Active Chromatin Sequence
The Active Chromatin Sequence (pronunciation: /ˈæk.tɪv ˈkrəʊ.mə.tɪn ˈsiː.kwəns/) is a specific sequence of DNA that is accessible and can be transcribed by RNA polymerase to produce RNA molecules. This sequence is part of the chromatin, the material that makes up chromosomes, which is typically less condensed and more transcriptionally active than other regions of the DNA.
Etymology
The term "Active Chromatin Sequence" is derived from the words "active", referring to the transcriptionally active state of the chromatin, "chromatin", a complex of DNA and protein that forms chromosomes within the nucleus of eukaryotic cells, and "sequence", referring to the specific order of nucleotides in a DNA molecule.
Related Terms
- Euchromatin: A type of chromatin that is rich in gene concentration and is often (but not always) under active transcription.
- Heterochromatin: A type of chromatin that is densely packed and often associated with low levels of transcription.
- Epigenetics: The study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself.
- Histone: Any of a group of basic proteins found in chromatin.
- Transcription (genetics): The first step of gene expression, in which a particular segment of DNA is copied into RNA by the enzyme RNA polymerase.
See Also
External links
- Medical encyclopedia article on Active chromatin sequence
- Wikipedia's article - Active chromatin sequence
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