Alphamethadol
Alphamethadol
Alphamethadol (pronunciation: al-fa-me-tha-dol) is a synthetic opioid analgesic, similar in structure and effects to methadone. It is used in the treatment of severe pain and in maintenance programs for opioid addiction.
Etymology
The term "Alphamethadol" is derived from the Greek letter "alpha", indicating the first in a series, and "methadone", the opioid analgesic from which it is synthesized.
Pharmacology
Alphamethadol is a potent agonist at the mu-opioid receptor, the primary site of action for most opioid drugs. It also has activity at the delta-opioid receptor and the kappa-opioid receptor, which may contribute to its analgesic and addictive properties.
Clinical Use
Alphamethadol is used in the treatment of severe pain, particularly in patients who have developed tolerance to other opioids. It is also used in maintenance programs for patients with opioid addiction, as it can help to reduce withdrawal symptoms and cravings.
Side Effects
Like other opioids, Alphamethadol can cause a range of side effects, including nausea, vomiting, constipation, and respiratory depression. It can also cause physical dependence and addiction with long-term use.
Related Terms
- Opioid
- Methadone
- Mu-opioid receptor
- Delta-opioid receptor
- Kappa-opioid receptor
- Physical dependence
- Addiction
External links
- Medical encyclopedia article on Alphamethadol
- Wikipedia's article - Alphamethadol
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