Ameloblastin
Ameloblastin
Ameloblastin (pronounced: a-melo-blast-in), also known as AMBN, is a protein that in humans is encoded by the AMBN gene. It is a crucial component in the development and formation of tooth enamel.
Etymology
The term "Ameloblastin" is derived from the Greek words "amelos" meaning enamel and "blastos" meaning germ. It was named for its role in the formation of tooth enamel by ameloblast cells.
Function
Ameloblastin is a member of the amelogenin family of extracellular matrix proteins. They are involved in biomineralization during tooth enamel development. Research has shown that mutations in the AMBN gene are associated with amelogenesis imperfecta, a congenital disorder that disrupts the formation of enamel.
Related Terms
- Ameloblast: A cell that produces enamel during the development of teeth.
- Amelogenin: A protein involved in the growth and development of tooth enamel.
- Amelogenesis: The process of forming enamel on teeth.
- Amelogenesis imperfecta: A group of rare genetic conditions affecting the structure and appearance of enamel.
See Also
- Dentin: The hard, dense, bony tissue forming the bulk of a tooth beneath the enamel.
- Odontoblast: A cell in the pulp of teeth, involved in the formation of dentin.
External links
- Medical encyclopedia article on Ameloblastin
- Wikipedia's article - Ameloblastin
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