Anaplasma phagocytophilum
Anaplasma phagocytophilum
Anaplasma phagocytophilum (pronunciation: an-uh-plaz-muh fag-oh-sy-toh-fill-uhm) is a gram-negative bacteria that is known to cause the disease human granulocytic anaplasmosis. It is a rickettsial pathogen of the family Anaplasmataceae.
Etymology
The term Anaplasma is derived from the Greek words ana meaning "up, back, again" and plasma meaning "something formed or molded". The term phagocytophilum is derived from the Greek words phagein meaning "to eat", kytos meaning "hollow, a vessel" and philos meaning "loving".
Description
Anaplasma phagocytophilum is an obligate intracellular bacteria that primarily infects neutrophils, a type of white blood cell. It is transmitted to humans through the bite of an infected black-legged tick, also known as the deer tick.
Symptoms
In humans, Anaplasma phagocytophilum causes human granulocytic anaplasmosis, which is characterized by fever, headache, muscle aches, and fatigue. In severe cases, it can cause leukopenia, thrombocytopenia, and elevated liver enzymes.
Diagnosis and Treatment
Diagnosis is typically made through serology or polymerase chain reaction (PCR) testing. Treatment usually involves the antibiotic doxycycline.
Related Terms
External links
- Medical encyclopedia article on Anaplasma phagocytophilum
- Wikipedia's article - Anaplasma phagocytophilum
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