Anti-idiotype vaccine

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Anti-idiotype Vaccine

Anti-idiotype vaccine (pronunciation: an-tee-eye-do-type vak-seen) is a type of vaccine that is designed to stimulate an immune response against idiotypes, which are unique regions on antibody molecules.

Etymology

The term "anti-idiotype vaccine" is derived from the words "anti", meaning against, "idiotype", referring to a unique set of antigenic determinants of the variable portion of an antibody, and "vaccine", a substance used to stimulate the production of antibodies and provide immunity against diseases.

Definition

An anti-idiotype vaccine is a type of cancer vaccine that is designed to stimulate the immune system to attack cancer cells. It does this by targeting idiotype, a unique set of antigenic determinants of the variable portion of an antibody. The vaccine is created by producing an antibody that binds to the idiotype on the cancer cells. This anti-idiotype antibody is then used to create the vaccine.

Related Terms

  • Idiotype: The unique set of antigenic determinants of the variable portion of an antibody.
  • Antibody: A blood protein produced in response to and counteracting a specific antigen.
  • Cancer vaccine: A vaccine that either treats existing cancer or prevents development of a cancer.
  • Immune response: The reaction of the cells and fluids of the body to the presence of a substance which is not recognized as a constituent of the body itself.

See Also

External links

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