Atoltivimab
Atoltivimab
Atoltivimab (pronunciation: a-tol-ti-vi-mab) is a monoclonal antibody designed for the treatment of Zaire ebolavirus, more commonly known as the Ebola virus. It is one of the three antibodies that make up the Ebola virus disease treatment regimen known as REGN-EB3 or Inmazeb.
Etymology
The name "Atoltivimab" follows the World Health Organization (WHO) guidelines for the International Nonproprietary Names (INN) of monoclonal antibodies. The "-mab" suffix indicates it is a monoclonal antibody, while the prefix "Atolti-" does not have a specific meaning and is used for distinction.
Usage
Atoltivimab is used in combination with Maftivimab and Odesivimab to form the drug Inmazeb, which is administered intravenously. This combination is used for the treatment of infection caused by Zaire ebolavirus in adult and pediatric patients, including newborns of mothers who have tested positive for the virus.
Related Terms
- Monoclonal antibody: A type of protein made in the lab that can bind to substances in the body, including cancer cells. Atoltivimab is a monoclonal antibody.
- Zaire ebolavirus: A deadly virus that is primarily transmitted between humans through direct contact with blood, secretions, organs or other bodily fluids. Atoltivimab is used to treat this virus.
- Ebola virus disease: A severe, often fatal illness in humans caused by the Ebola virus. Atoltivimab is part of a treatment regimen for this disease.
- REGN-EB3: A combination of three monoclonal antibodies (atoltivimab, maftivimab, and odesivimab) used to treat Ebola virus disease.
- Inmazeb: The brand name for the combination of atoltivimab, maftivimab, and odesivimab.
External links
- Medical encyclopedia article on Atoltivimab
- Wikipedia's article - Atoltivimab
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