BMS-345541
BMS-345541
BMS-345541 (pronunciation: B-M-S-Three-Four-Five-Five-Four-One) is a highly selective inhibitor of IKK (IκB kinase). It is often used in scientific research to study the role of NF-κB in various biological processes.
Etymology
The term "BMS-345541" is a compound name derived from the initials of the pharmaceutical company Bristol-Myers Squibb (BMS) and the unique identifier number 345541 assigned to this specific inhibitor during its development.
Usage
BMS-345541 is used in scientific research to inhibit the activity of IKK, a kinase that plays a crucial role in the activation of NF-κB. By inhibiting IKK, BMS-345541 can prevent the activation of NF-κB, allowing researchers to study the effects of NF-κB inhibition on various biological processes.
Related Terms
- IKK: IκB kinase, the enzyme that BMS-345541 inhibits.
- NF-κB: Nuclear factor kappa-light-chain-enhancer of activated B cells, a protein complex that controls transcription of DNA, cytokine production and cell survival.
- Inhibitor: A substance that slows down or prevents a particular chemical reaction or other process, or that reduces the activity of a particular reactant, catalyst, or enzyme.
- Kinase: An enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates.
External links
- Medical encyclopedia article on BMS-345541
- Wikipedia's article - BMS-345541
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