Beta-1 adrenergic receptor

The Beta-1 adrenergic receptor (pronounced as: bay-tuh one ad-ren-er-gic re-sep-tor), also known as ADRB1, is a type of adrenergic receptor that is encoded by the ADRB1 gene in humans.

Etymology

The term "Beta-1 adrenergic receptor" is derived from the Greek words "βήτα" (beta), which is the second letter of the Greek alphabet, and "adrenergic", which refers to the action of the neurotransmitter epinephrine (adrenaline) and norepinephrine (noradrenaline). The "1" in "Beta-1" indicates that it is one subtype of beta adrenergic receptors.

Function

Beta-1 adrenergic receptors are primarily located in the heart and kidneys. They play a crucial role in the regulation of heart function by mediating the effects of catecholamines, particularly epinephrine and norepinephrine. Activation of Beta-1 adrenergic receptors leads to increased heart rate, contractility, and conduction velocity, which are all essential for the body's fight-or-flight response.

Related Terms

Adrenergic receptor: A class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine and epinephrine.
Epinephrine: Also known as adrenaline, a hormone and neurotransmitter that plays a key role in the body's fight-or-flight response.
Norepinephrine: Also known as noradrenaline, a hormone and neurotransmitter that is important for attentiveness, emotions, sleeping, dreaming, and learning.
Catecholamines: A group of hormones produced in the body, including epinephrine, norepinephrine, and dopamine.

External links

Medical encyclopedia article on Beta-1 adrenergic receptor
Wikipedia's article - Beta-1 adrenergic receptor

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Beta-1 adrenergic receptor