CYP1A1
CYP1A1
CYP1A1 (pronounced "sip-one-ay-one"), also known as Cytochrome P450 1A1, is an enzyme that in humans is encoded by the CYP1A1 gene.
Etymology
The term CYP1A1 is derived from the larger family of cytochrome P450 enzymes it belongs to. The "CYP" stands for "CYtochrome P450", while the "1A1" denotes its specific subtype.
Function
CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. These enzymes are involved in the metabolism of a variety of compounds, including drugs, toxins, and endogenous substances. Specifically, CYP1A1 is involved in the metabolism of certain polycyclic aromatic hydrocarbons, some of which are found in cigarette smoke and can lead to the formation of DNA adducts, potentially causing mutations and cancer.
Related Terms
- Cytochrome P450: The superfamily of enzymes that CYP1A1 belongs to.
- Enzyme: Proteins that act as biological catalysts.
- Metabolism: The set of life-sustaining chemical reactions in organisms.
- Polycyclic aromatic hydrocarbons: A class of chemicals that CYP1A1 helps to metabolize.
- DNA adducts: Pieces of DNA covalently bonded to a cancer-causing chemical.
- Mutation: A change in the DNA sequence that can lead to disease.
- Cancer: A group of diseases involving abnormal cell growth.
External links
- Medical encyclopedia article on CYP1A1
- Wikipedia's article - CYP1A1
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