Cerebral perfusion pressure
Cerebral Perfusion Pressure
Cerebral perfusion pressure (CPP) is the net pressure gradient causing cerebral blood flow to the brain (brain perfusion). It is the difference between the Mean Arterial Pressure (MAP), and the Intracranial Pressure (ICP).
Pronunciation
Cerebral: /səˈriːbrəl/ Perfusion: /pərˈfjuːʒ(ə)n/ Pressure: /ˈprɛʃə/
Etymology
The term Cerebral is derived from the Latin word 'cerebrum' which means brain. Perfusion originates from the Latin word 'perfusio', meaning 'to pour over'. Pressure is derived from the Latin word 'pressura', meaning 'action of pressing'.
Definition
Cerebral perfusion pressure is crucial in maintaining the blood flow to the brain. It is calculated by subtracting the ICP from the MAP. The normal CPP value ranges from 60 to 80 mm Hg, and a CPP less than 50 mm Hg can result in cerebral ischemia or cerebral infarction.
Calculation
The CPP is calculated using the formula: CPP = MAP - ICP
Importance
Maintaining an adequate CPP is crucial in the management of patients with traumatic brain injury as it ensures sufficient blood flow to the brain, preventing cerebral ischemia and subsequent brain damage.
Related Terms
- Intracranial pressure
- Mean arterial pressure
- Cerebral ischemia
- Cerebral infarction
- Traumatic brain injury
External links
- Medical encyclopedia article on Cerebral perfusion pressure
- Wikipedia's article - Cerebral perfusion pressure
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