Cisapride

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Cisapride

Cisapride (pronounced as /sɪˈsæpraɪd/) is a gastroprokinetic agent that enhances the motility of the gastrointestinal tract by increasing the release of acetylcholine from the myenteric plexus. It was developed in the late 20th century and was widely used for the treatment of gastroesophageal reflux disease (GERD) and other conditions related to reduced gastrointestinal motility.

Etymology

The term "Cisapride" is derived from the Latin word 'cis', meaning 'on this side', and 'apride', which is a non-standard suffix used in pharmacology to denote agents that stimulate certain types of receptors or physiological responses. In this case, 'apride' refers to the drug's ability to stimulate gastrointestinal motility.

Usage

Cisapride is primarily used in the treatment of gastroesophageal reflux disease (GERD), a condition in which stomach acid frequently flows back into the tube connecting your mouth and stomach (esophagus). It is also used to treat other conditions related to reduced gastrointestinal motility, such as gastroparesis (delayed gastric emptying) and chronic constipation.

Side Effects

Like all medications, Cisapride can cause side effects. The most common side effects include abdominal pain, diarrhea, and nausea. In rare cases, Cisapride can cause serious heart problems, including arrhythmia and QT prolongation, which is why its use is now restricted in many countries.

Related Terms

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