Cloxestradiol acetate

Cloxestradiol acetate (pronunciation: klox-es-tra-diol a-ce-tate) is a synthetic estrogen that is used in hormone replacement therapy. It is a derivative of estradiol, the primary female sex hormone.

Etymology

The term "Cloxestradiol" is derived from the parent compound estradiol, with the prefix "clox" indicating the addition of a chlorine atom and an acetoxy group. The suffix "acetate" refers to the acetic acid component of the compound.

Pharmacology

Cloxestradiol acetate is a prodrug of estradiol, meaning it is metabolized in the body to produce estradiol. It is used in hormone replacement therapy to treat symptoms of menopause, such as hot flashes and vaginal dryness. It can also be used to treat certain conditions in women who have a deficiency in estrogen, such as osteoporosis and certain types of breast cancer.

Side Effects

Like other estrogens, cloxestradiol acetate can have a number of side effects, including nausea, bloating, breast tenderness, and an increased risk of blood clots and stroke. It is also associated with an increased risk of certain types of cancer, including breast cancer and endometrial cancer.

Related Terms

• Estradiol
• Estrogen
• Hormone replacement therapy
• Osteoporosis
• Breast cancer
• Endometrial cancer

External links

• Medical encyclopedia article on Cloxestradiol acetate
• Wikipedia's article - Cloxestradiol acetate

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