Cobicistat

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Cobicistat

Cobicistat (pronounced as koh-bi-SIS-tat) is a pharmaceutical drug that is used to enhance the effectiveness of certain antiretroviral drugs used in the treatment of HIV and AIDS. It is a type of pharmacokinetic enhancer that works by inhibiting the action of an enzyme known as cytochrome P450 3A (CYP3A), which is involved in the metabolism of many drugs. By inhibiting CYP3A, cobicistat increases the concentration of these drugs in the body, thereby enhancing their effectiveness.

Etymology

The name "cobicistat" is derived from the chemical name of the compound, which is "COBIcistat", where "COBI" stands for "CYP3A Inhibitor" and "cistat" is a suffix used in pharmaceutical nomenclature to denote a type of drug that inhibits a specific enzyme.

Related Terms

  • Antiretroviral therapy: A type of treatment for HIV and AIDS that uses drugs to prevent the virus from replicating in the body.
  • Pharmacokinetics: The study of how drugs are absorbed, distributed, metabolized, and excreted by the body.
  • Cytochrome P450: A family of enzymes involved in the metabolism of many drugs and other substances in the body.
  • Protease inhibitor: A type of antiretroviral drug that works by inhibiting the action of an enzyme called protease, which is needed by HIV to replicate.

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