Cockcroft
Cockcroft-Gault Equation
The Cockcroft-Gault Equation (pronounced: Cock-croft Gault Equation) is a formula that allows the estimation of the Glomerular Filtration Rate (GFR), which is a measure of the kidney function. The equation was named after the scientists Donald W. Cockcroft and Matthew H. Gault who first published the formula in 1976.
Etymology
The term "Cockcroft-Gault Equation" is derived from the names of the two scientists who developed the formula, Donald W. Cockcroft and Matthew H. Gault. Both were nephrologists, a specialty of medicine and pediatrics that concerns itself with the study of the kidneys.
Definition
The Cockcroft-Gault Equation is defined as follows:
- CrCl = [(140 - age) x weight in kg x (0.85 if female)] / (72 x serum creatinine)
Where:
- CrCl is the Creatinine Clearance
- age is the patient's age in years
- weight is the patient's weight in kilograms
- serum creatinine is the patient's serum creatinine level in mg/dL
Related Terms
- Creatinine Clearance: The volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR.
- Glomerular Filtration Rate: The volume of fluid that the kidneys filter from the blood per unit time.
- Nephrology: The branch of medicine that deals with the physiology and diseases of the kidneys.
- Serum Creatinine: A blood measurement that is widely used to estimate the functioning of the kidneys.
External links
- Medical encyclopedia article on Cockcroft
- Wikipedia's article - Cockcroft
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