Conjugated estrogens/norgestrel

Conjugated estrogens/norgestrel

Conjugated estrogens/norgestrel (/kɒnˈdʒʊɡeɪtɪd ˈɛstrədʒənz/ /nɔːrˈdʒɛstrəl/) is a combination medication used in hormone replacement therapy (HRT).

Etymology

The term "conjugated estrogens" refers to a mixture of estrogen hormones, while "norgestrel" is a synthetic progestogen. The term "conjugated" is derived from the Latin conjugare, meaning "to join together". The term "estrogen" is derived from the Greek oistros, meaning "gadfly" or "frenzy", and -gen, meaning "producer of". The term "norgestrel" is derived from nor- (a prefix used in organic chemistry to denote a structure containing one less carbon atom than the parent compound) and gestrel (a suffix used to denote synthetic progestogens).

Pharmacology

Conjugated estrogens are a form of estrogen hormones used to replace lower estrogen levels in the body. They are often used in combination with a progestogen, such as norgestrel, to prevent endometrial hyperplasia.

Uses

Conjugated estrogens/norgestrel is used in the treatment of symptoms of menopause, such as hot flashes and vaginal dryness. It is also used in the prevention of osteoporosis in postmenopausal women, and in the treatment of certain cancers in both men and women.

Side Effects

Possible side effects of conjugated estrogens/norgestrel include nausea, vomiting, headache, bloating, breast tenderness, or weight changes.

Related Terms

• Estrogen
• Progestogen
• Hormone replacement therapy
• Menopause
• Osteoporosis
• Endometrial hyperplasia

External links

• Medical encyclopedia article on Conjugated estrogens/norgestrel
• Wikipedia's article - Conjugated estrogens/norgestrel

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