Corneal cross-linking
Corneal Cross-Linking
Corneal cross-linking (pronunciation: /ˈkɔːrniəl ˈkrɒs ˈlɪŋkɪŋ/), also known as CXL, Keratoconus treatment, or Corneal collagen cross-linking, is a medical procedure that uses ultraviolet (UV) light and a photosensitizer to strengthen chemical bonds in the cornea.
Etymology
The term "corneal cross-linking" derives from the procedure's effect on the structural proteins in the cornea. "Cross-linking" refers to the formation of strong, direct links between the collagen fibers in the cornea, which helps to stabilize and strengthen the cornea's structure.
Procedure
Corneal cross-linking is performed under local anesthesia. The procedure involves removing the outer layer of the cornea, called the epithelium, to allow for better penetration of the photosensitizer, riboflavin. After the application of riboflavin, the cornea is then exposed to UV light. This activates the riboflavin and leads to the formation of bonds between the collagen fibers in the cornea.
Indications
Corneal cross-linking is primarily used to treat keratoconus, a degenerative disorder that causes a conical shape of the cornea. It may also be used to treat other conditions that cause corneal ectasia, such as pellucid marginal degeneration and post-LASIK ectasia.
Risks and Complications
As with any medical procedure, corneal cross-linking carries potential risks and complications. These may include infection, corneal haze, and changes in corneal topography. In rare cases, it can lead to significant vision loss.
Related Terms
External links
- Medical encyclopedia article on Corneal cross-linking
- Wikipedia's article - Corneal cross-linking
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