Decoy cells

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Decoy cells (pronunciation: /ˈdiːkɔɪ sɛlz/) are a type of urinary cell that can be found in the urine of individuals with certain viral infections, particularly those caused by the BK virus and JC virus.

Etymology

The term "decoy cell" is derived from the cells' deceptive appearance. They resemble normal epithelial cells, but upon closer examination, they are found to be filled with viral inclusions.

Description

Decoy cells are large, irregularly shaped cells with a clear cytoplasm and a large, darkly stained nucleus. The nucleus contains ground-glass inclusions, which are indicative of a viral infection. These cells are called "decoy" because they mimic the appearance of normal epithelial cells, thereby "decoying" or misleading the observer.

Clinical significance

The presence of decoy cells in the urine is a sign of a viral infection, most commonly the BK virus or JC virus. These viruses can cause serious illness in individuals with weakened immune systems, such as those who have undergone organ transplantation or are living with HIV/AIDS. The detection of decoy cells in the urine can help in the early diagnosis and treatment of these infections.

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