Diarylpyrimidines

Diarylpyrimidines (pronunciation: die-aryl-pyrimidines) are a class of antiretroviral drugs used in the treatment of HIV infections.

Etymology

The term "Diarylpyrimidines" is derived from the chemical structure of these compounds, which consist of a pyrimidine ring flanked by two aryl groups.

Usage

Diarylpyrimidines are non-nucleoside reverse transcriptase inhibitors (NNRTIs). They work by inhibiting the reverse transcriptase enzyme, which is crucial for the replication of HIV. This class of drugs includes compounds such as Etravirine and Rilpivirine, which are commonly used in antiretroviral therapy regimens.

Related Terms

Antiretroviral therapy: The use of medications to manage HIV and prevent its progression to AIDS.
Reverse transcriptase: An enzyme that converts RNA into DNA, a critical step in the replication of HIV.
Etravirine: A diarylpyrimidine antiretroviral drug used in the treatment of HIV.
Rilpivirine: Another diarylpyrimidine antiretroviral drug used in the treatment of HIV.

External links

Medical encyclopedia article on Diarylpyrimidines
Wikipedia's article - Diarylpyrimidines

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Diarylpyrimidines