ED50
ED50
ED50 (pronounced as E-D-fifty), also known as the Effective Dose 50%, is a standard dose that is used in pharmacology and toxicology to measure the effectiveness of a drug or toxin. The term is derived from the phrase "Effective Dose for 50% of the population".
Etymology
The term ED50 is an abbreviation of "Effective Dose 50%". The term is used to denote the dose of a drug or toxin that produces a therapeutic effect in 50% of the population, or that produces a response halfway between the baseline and maximum after a specified exposure time.
Definition
In pharmacology, the ED50 is a standard measure that is used to quantify the effect of a drug treatment. It is the dose at which 50% of the population experiences the drug's therapeutic effect. This measure is used in dose-response studies to determine the relative potency of drugs.
In toxicology, the ED50 is used to measure the toxicity of a substance. It is the dose that causes a harmful effect in 50% of the population.
Related Terms
- LD50: The lethal dose for 50% of the population. This is the dose of a substance that is lethal to 50% of a test population.
- TD50: The toxic dose for 50% of the population. This is the dose of a substance that will cause a toxic effect in 50% of a test population.
- Therapeutic index: The ratio of the toxic dose to the therapeutic dose of a drug, used as a measure of the relative safety of the drug for a particular treatment.
See Also
External links
- Medical encyclopedia article on ED50
- Wikipedia's article - ED50
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