Elastosis perforans serpiginosa
Elastosis Perforans Serpiginosa (pronunciation: e-las-to-sis per-fo-rans ser-pi-gi-no-sa) is a rare skin disorder classified under the broader category of connective tissue diseases.
Etymology
The term 'Elastosis Perforans Serpiginosa' is derived from three Latin words: 'elastos' meaning elastic, 'perforans' referring to perforating, and 'serpiginosa' meaning creeping.
Definition
Elastosis Perforans Serpiginosa (EPS) is a rare condition characterized by the elimination of abnormal elastic tissue through the epidermis. It is often associated with D-penicillamine therapy, Down syndrome, and Ehlers-Danlos syndrome.
Symptoms
The primary symptom of EPS is the presence of small, keratotic papules that often arrange themselves in a serpiginous or annular pattern. These papules are typically found on the face, neck, and upper extremities.
Diagnosis
Diagnosis of EPS is primarily based on clinical findings and histopathological examination. The histopathological features of EPS include transepidermal elimination of altered elastic fibers.
Treatment
Treatment options for EPS include cryotherapy, topical retinoids, and laser therapy. However, the condition is often resistant to treatment and may recur.
See Also
External links
- Medical encyclopedia article on Elastosis perforans serpiginosa
- Wikipedia's article - Elastosis perforans serpiginosa
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