Endothelin-2
Endothelin-2
Endothelin-2 (pronunciation: en-doh-THE-lin-2) is a peptide that is part of the endothelin family. It is a potent vasoconstrictor and plays a significant role in various physiological and pathological processes.
Etymology
The term "Endothelin" is derived from the word "endothelium", which refers to the thin layer of cells that lines the interior surface of blood vessels. The number "2" signifies that it is the second member of the endothelin family to be discovered.
Function
Endothelin-2 is produced primarily by endothelial cells and has a variety of functions. It is involved in the regulation of blood pressure and blood flow, the modulation of inflammation, and the promotion of cell proliferation and cell migration. It also plays a role in the development of certain diseases, such as hypertension, atherosclerosis, and heart failure.
Related Terms
- Endothelin-1: The first member of the endothelin family to be discovered. It has similar functions to endothelin-2.
- Endothelin-3: The third member of the endothelin family. It has distinct functions and is primarily involved in the development and function of the nervous system.
- Endothelin Receptor: A type of receptor that binds to endothelins and mediates their effects.
- Endothelin Converting Enzyme: An enzyme that converts big endothelins to their active forms.
External links
- Medical encyclopedia article on Endothelin-2
- Wikipedia's article - Endothelin-2
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