Epigenetic alteration
Epigenetic alteration | |
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Term | Epigenetic alteration |
Short definition | epigenetic alteration (EH-pih-jeh-NEH-tik ALL-teh-RAY-shun) A change in the chemical structure of DNA that does not alter the DNA coding sequence. Epigenetic changes occur in the body when chemical groups called methyl groups are added or removed from DNA, or when changes are made to proteins called histones, which bind to DNA in chromosomes. |
Type | Cancer terms |
Specialty | Oncology |
Language | English |
Source | NCI |
Comments |
epigenetic alteration - (pronounced) (EH-pih-jeh-NEH-tik ALL-teh-RAY-shun) A change in the chemical structure of DNA that does not alter the DNA coding sequence. Epigenetic changes occur in the body when chemical groups called methyl groups are added or removed from DNA, or when changes are made to proteins called histones, which bind to DNA in chromosomes. These changes can occur with age and exposure to environmental factors such as diet, exercise, medications, and chemicals. They can affect a person's risk of disease and can be passed from parent to child. Also called epigenetic variant and epimutation
External links
- Medical encyclopedia article on Epigenetic alteration
- Wikipedia's article - Epigenetic alteration
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