EsiRNA
EsiRNA
EsiRNA (pronounced "eh-see-RNA"), also known as Endoribonuclease-prepared siRNAs, is a class of RNA molecules that are used in biological research to silence the expression of specific genes.
Pronunciation
- EsiRNA: /ɛsiːɑːrɛnɛɪ/
Etymology
The term "EsiRNA" is an acronym derived from "Endoribonuclease-prepared siRNAs". The term "siRNA" stands for "small interfering RNA", a type of RNA molecule that interferes with the expression of specific genes.
Definition
EsiRNAs are a type of siRNA that are prepared using an endoribonuclease enzyme. This process results in a pool of siRNAs that target different regions of the same gene, increasing the likelihood of effective gene silencing. EsiRNAs are commonly used in RNA interference (RNAi) experiments to study the function of specific genes.
Related Terms
- RNA: Ribonucleic acid, a molecule similar to DNA that plays a crucial role in gene expression.
- siRNA: Small interfering RNA, a type of RNA molecule that interferes with the expression of specific genes.
- RNA interference (RNAi): A biological process in which RNA molecules inhibit gene expression.
- Endoribonuclease: An enzyme that cleaves RNA molecules.
See Also
External links
- Medical encyclopedia article on EsiRNA
- Wikipedia's article - EsiRNA
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