Globozoospermia
Globozoospermia
Globozoospermia (pronounced: glo-bo-zoo-sper-mia) is a rare condition in males characterized by the production of round-headed spermatozoa. It is associated with male infertility due to the inability of the sperm to penetrate the egg during fertilization.
Etymology
The term "Globozoospermia" is derived from the Latin words "globus" meaning globe or sphere, and "zoospermia" meaning animal sperm.
Causes
Globozoospermia is often caused by genetic mutations, particularly in the DPY19L2 gene. Other potential causes include improper acrosome formation and issues with sperm maturation.
Symptoms
The primary symptom of globozoospermia is infertility. Men with this condition may not exhibit any other symptoms.
Diagnosis
Diagnosis of globozoospermia is typically made through a semen analysis, which can identify the characteristic round-headed sperm. Genetic testing may also be used to identify mutations in the DPY19L2 gene.
Treatment
Treatment options for globozoospermia include Intracytoplasmic Sperm Injection (ICSI) and Testicular Sperm Extraction (TESE). These treatments involve the direct injection of sperm into an egg or the extraction of sperm directly from the testes.
Related Terms
- Infertility
- DPY19L2
- Semen analysis
- Intracytoplasmic Sperm Injection (ICSI)
- Testicular Sperm Extraction (TESE)
External links
- Medical encyclopedia article on Globozoospermia
- Wikipedia's article - Globozoospermia
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