Gray zone lymphoma
Gray zone lymphoma
Gray zone lymphoma (GZL), also known as lymphoma of the gray zone, is a rare type of lymphoma that shares characteristics with both Hodgkin's lymphoma and non-Hodgkin's lymphoma. The term "gray zone" refers to the ambiguous nature of this disease, as it does not fit neatly into either category.
Pronunciation
Gray zone lymphoma is pronounced as /ɡreɪ zoʊn lɪmˈfoʊmə/.
Etymology
The term "gray zone lymphoma" is derived from the English words "gray" and "zone", referring to the uncertain or intermediate nature of the disease, and "lymphoma", a term derived from the Greek words "lympho-" (meaning lymph) and "-oma" (meaning tumor).
Description
Gray zone lymphoma is characterized by a mixture of Reed-Sternberg cells typically seen in Hodgkin's lymphoma and the diffuse growth pattern of non-Hodgkin's lymphoma. It is often diagnosed in young adults and is more common in males than females. The most common sites of involvement are the mediastinum (the area between the lungs), lymph nodes, and spleen.
Symptoms
Symptoms of gray zone lymphoma can include fever, night sweats, weight loss, and fatigue. These are also known as B symptoms and are common in many types of lymphoma.
Treatment
Treatment for gray zone lymphoma typically involves chemotherapy, with or without radiation therapy. The choice of treatment depends on the stage of the disease, the patient's overall health, and other factors.
Prognosis
The prognosis for gray zone lymphoma varies widely and depends on several factors, including the stage of the disease, the patient's overall health, and the response to treatment.
Related Terms
- Lymphoma
- Hodgkin's lymphoma
- Non-Hodgkin's lymphoma
- Reed-Sternberg cells
- B symptoms
- Chemotherapy
- Radiation therapy
External links
- Medical encyclopedia article on Gray zone lymphoma
- Wikipedia's article - Gray zone lymphoma
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