H&E stain
H&E Stain
H&E stain or Hematoxylin and Eosin stain is a popular staining method in histology. It is named after the dyes hematoxylin and eosin, which are used in the staining process.
Pronunciation
H&E Stain: /ˈhɛməˌtoʊsɪlɪn ænd ˈiːsɪn steɪn/
Etymology
The term "H&E stain" is an abbreviation of the two dyes used in the process: hematoxylin and eosin. Hematoxylin is derived from the Greek words 'haima' and 'kyanos', meaning 'blood' and 'blue', respectively. Eosin is derived from the Greek word 'eos', meaning 'dawn', referring to the pink color it produces.
Description
H&E stain is the most widely used stain in medical diagnosis; for example, when a pathologist looks at a biopsy of a suspected cancer, the histological section is likely to be stained with H&E. Hematoxylin, which stains nuclei blue-purple, and eosin, which stains the cytoplasm and the extracellular connective tissue matrix pink, are used.
Related Terms
- Histology: The study of the microscopic structure of tissues.
- Pathologist: A medical professional who studies the causes and nature of diseases.
- Biopsy: A medical test involving the extraction of sample cells or tissues for examination.
- Cytoplasm: The material within a living cell, excluding the cell nucleus.
- Extracellular matrix: A three-dimensional network of extracellular macromolecules, such as collagen and glycoproteins, that provide structural and biochemical support to surrounding cells.
External links
- Medical encyclopedia article on H&E stain
- Wikipedia's article - H&E stain
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