Haber's rule
Haber's Rule is a principle in toxicology that states the product of the concentration of a poisonous gas and the time of exposure to it is a constant for a given degree of injury. It is named after Fritz Haber, a German chemist who won the Nobel Prize in Chemistry in 1918.
Pronunciation
Haber's Rule: /ˈhɑːbərz ˈruːl/
Etymology
The rule is named after Fritz Haber (1868-1934), a German chemist who won the Nobel Prize in Chemistry in 1918 for his development of a method to synthesize ammonia from nitrogen and hydrogen gases, known as the Haber-Bosch process. Haber also conducted significant research in the field of toxicology, leading to the formulation of this rule.
Definition
Haber's Rule is a principle in toxicology that states the product of the concentration (C) of a poisonous gas and the time (T) of exposure to it is a constant (k) for a given degree of injury. This can be expressed mathematically as:
C x T = k
This rule is used to estimate the lethal or harmful effects of exposure to toxic gases. It is based on the assumption that the total dose of a toxic gas, rather than the concentration or duration of exposure alone, determines the degree of harm caused.
Related Terms
- Toxicology: The study of the adverse effects of chemicals on living organisms.
- Haber-Bosch process: An industrial method for synthesizing ammonia from nitrogen and hydrogen gases.
- Dose-response relationship: The relationship between the dose of a drug or toxin and the effect it has on a living organism.
- Lethal dose: The amount of a substance that is sufficient to cause death in a living organism.
See Also
External links
- Medical encyclopedia article on Haber's rule
- Wikipedia's article - Haber's rule
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