Hypocortisolism

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Hypocortisolism (pronounced: hi-po-kor-ti-so-lizm) is a medical condition characterized by a deficiency in the production of cortisol by the adrenal glands.

Etymology

The term "Hypocortisolism" is derived from the Greek words "hypo" meaning "under" or "less", "corti" referring to the cortex of the adrenal glands where cortisol is produced, and "ism" denoting a condition or disease.

Definition

Hypocortisolism, also known as Addison's disease, is a disorder that occurs when the body produces insufficient amounts of certain hormones produced by your adrenal glands. In particular, it is characterized by a deficiency in the production of cortisol, a hormone that plays a crucial role in numerous body functions, including the body's response to stress and regulation of metabolism.

Symptoms

Symptoms of hypocortisolism can vary and may include fatigue, muscle weakness, loss of appetite, weight loss, low blood pressure, and sometimes darkening of the skin. The severity of the symptoms often depends on the extent of the cortisol deficiency.

Causes

Hypocortisolism can be caused by problems in the adrenal glands (primary hypocortisolism), in the pituitary gland (secondary hypocortisolism), or in the hypothalamus (tertiary hypocortisolism). It can also be induced by long-term use of corticosteroid medications.

Treatment

Treatment for hypocortisolism typically involves hormone replacement therapy to replace the insufficient hormones. The specific treatment plan will depend on the underlying cause of the hypocortisolism.

Related Terms

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