Imatinib
Imatinib (pronounced as i-ma-ti-nib) is a medication used primarily in the treatment of certain types of cancer.
Pronunciation
The pronunciation of Imatinib is /ɪˈmætɪnɪb/.
Etymology
The name "Imatinib" is derived from its chemical name, 4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl)benzamide.
Usage
Imatinib is used to treat chronic myelogenous leukemia (CML) and acute lymphoblastic leukemia (ALL) that are positive for the Philadelphia chromosome. It is also used in treating gastrointestinal stromal tumors (GISTs), hypereosinophilic syndrome (HES), and dermatofibrosarcoma protuberans when surgery is not an option.
Mechanism of Action
Imatinib works by inhibiting the growth of certain cells that are involved in the development of cancer. It does this by blocking the action of an abnormal protein that signals cancer cells to multiply.
Side Effects
Common side effects of Imatinib include nausea, vomiting, diarrhea, and muscle cramps. Serious side effects may include fluid retention, bleeding, heart failure, and liver disease.
Related Terms
- Chronic Myelogenous Leukemia (CML)
- Acute Lymphoblastic Leukemia (ALL)
- Gastrointestinal Stromal Tumors (GISTs)
- Hypereosinophilic Syndrome (HES)
- Dermatofibrosarcoma Protuberans
External links
- Medical encyclopedia article on Imatinib
- Wikipedia's article - Imatinib
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