Imatinib

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Imatinib (pronounced as i-ma-ti-nib) is a medication used primarily in the treatment of certain types of cancer.

Pronunciation

The pronunciation of Imatinib is /ɪˈmætɪnɪb/.

Etymology

The name "Imatinib" is derived from its chemical name, 4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl)benzamide.

Usage

Imatinib is used to treat chronic myelogenous leukemia (CML) and acute lymphoblastic leukemia (ALL) that are positive for the Philadelphia chromosome. It is also used in treating gastrointestinal stromal tumors (GISTs), hypereosinophilic syndrome (HES), and dermatofibrosarcoma protuberans when surgery is not an option.

Mechanism of Action

Imatinib works by inhibiting the growth of certain cells that are involved in the development of cancer. It does this by blocking the action of an abnormal protein that signals cancer cells to multiply.

Side Effects

Common side effects of Imatinib include nausea, vomiting, diarrhea, and muscle cramps. Serious side effects may include fluid retention, bleeding, heart failure, and liver disease.

Related Terms

External links

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