Janus

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Janus

Janus (/ˈdʒeɪnəs/; Latin: IANVS (Iānus)) is a term used in various fields of medicine. The term is derived from the Roman god Janus, who is often depicted with two faces, symbolizing beginnings, transitions, time, duality, doorways, passages, and endings.

In Medicine

In medicine, the term 'Janus' is often used to describe conditions or phenomena that have two distinct or opposing aspects. For example, Janus Kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway.

Janus Kinase

Janus Kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. They are named after the two-faced Roman god Janus because they possess two near-identical phosphate-transferring domains. One domain exhibits the kinase activity, while the other negatively regulates the kinase activity of the first.

Janus Phenomenon

The Janus Phenomenon is a term used in pharmacology to describe the paradoxical effects of some drugs, where they can have both beneficial and harmful effects. This is named after the Roman god Janus, symbolizing the dual nature of these effects.

Related Terms

  • Janus Kinase Inhibitors: A class of drugs used in the treatment of several diseases such as rheumatoid arthritis and psoriasis.
  • Janus Green B: A basic dye used in histology.
  • Janus Particles: Particles with two or more different surface properties, used in various fields including medicine and materials science.

See Also

External links

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