Kveim test

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Kveim Test

The Kveim test (pronounced: /kvaɪm/), also known as Kveim-Siltzbach test, is a skin test used in the diagnosis of sarcoidosis, a systemic inflammatory disease that affects multiple organs in the body. The test is named after the Norwegian pathologist Morten Ansgar Kveim and the American physician Louis Siltzbach who contributed to its development.

Etymology

The term "Kveim" is derived from the surname of Norwegian pathologist Morten Ansgar Kveim, who first introduced the test in 1941. The term "Siltzbach" is derived from the surname of American physician Louis Siltzbach, who further refined the test in the 1960s.

Procedure

The Kveim test involves injecting a purified protein derivative from the spleen of a patient with known sarcoidosis into the skin of a patient suspected of having the disease. If the patient has sarcoidosis, a granuloma will form at the injection site within 4 to 6 weeks.

Related Terms

  • Sarcoidosis: A systemic inflammatory disease that affects multiple organs in the body.
  • Granuloma: A small area of inflammation due to tissue injury.
  • Skin test: A method of testing for allergic or immune reactions to substances by applying them to the skin.
  • Morten Ansgar Kveim: A Norwegian pathologist who first introduced the Kveim test.
  • Louis Siltzbach: An American physician who further refined the Kveim test.

See Also

External links

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