MDX-010
MDX-010 | |
---|---|
Term | MDX-010 |
Short definition | MDX-010 - A drug that binds to the protein CTLA-4 to help immune cells kill cancer cells better and is used to treat many different types of cancer. These include cancers that have certain mutations (changes) in genes involved in DNA repair. |
Type | Cancer terms |
Specialty | Oncology |
Language | English |
Source | NCI |
Comments |
MDX-010 - A drug that binds to the protein CTLA-4 to help immune cells kill cancer cells better and is used to treat many different types of cancer. These include cancers that have certain mutations (changes) in genes involved in DNA repair. MDX-010 is used alone or with other medicines to treat certain types of colon cancer, esophageal cancer, hepatocellular carcinoma (a type of liver cancer), malignant pleural mesothelioma, melanoma, non-small cell lung cancer and renal cell carcinoma (a type of kidney cancer). It is also being studied in the treatment of other types of cancer. MDX-010 can block CTLA-4 and help the immune system kill cancer cells. It's a type of monoclonal antibody and a type of immune checkpoint inhibitor. Also called ipilimumab and yervoy
External links
- Medical encyclopedia article on MDX-010
- Wikipedia's article - MDX-010
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