MSH2 gene
MSH2 gene | |
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Term | MSH2 gene |
Short definition | MSH2 gene - gene that produces a protein involved in repairing DNA errors that can occur when DNA is copied in a cell. Mutations (changes) in the MSH2 gene can cause unrepaired errors in the DNA to accumulate in the cell, which can lead to abnormal cell growth and cancer. |
Type | Cancer terms |
Specialty | Oncology |
Language | English |
Source | NCI |
Comments |
MSH2 gene - gene that produces a protein involved in repairing DNA errors that can occur when DNA is copied in a cell. Mutations (changes) in the MSH2 gene can cause unrepaired errors in the DNA to accumulate in the cell, which can lead to abnormal cell growth and cancer. MSH2 gene mutations have been found in the hereditary diseases Lynch syndrome and Muir-Torre syndrome. People with these disorders have an increased risk of developing colon and other cancers. The MSH2 gene is a type of DNA mismatch repair (MMR) gene
External links
- Medical encyclopedia article on MSH2 gene
- Wikipedia's article - MSH2 gene
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