Mansonella perstans
Mansonella perstans
Mansonella perstans (/mænsəˈnɛlə pɜːrˈstæns/) is a parasitic nematode that causes a tropical disease known as mansonelliasis. The term "Mansonella" is derived from the name of Sir Patrick Manson, a British physician who made significant contributions to the field of tropical medicine, while "perstans" is a Latin word meaning "persisting", referring to the long lifespan of the adult worms in the human body.
Life Cycle
The life cycle of Mansonella perstans begins when an infected biting midge (genus Culicoides) or a blackfly (genus Simulium) deposits larvae onto the skin of a human host during a blood meal. The larvae penetrate the skin and enter the lymphatic system, where they mature into adult worms. The adult worms produce microfilariae, which circulate in the peripheral blood and can be ingested by a biting midge or blackfly during a blood meal, thus continuing the cycle.
Symptoms and Diagnosis
Infection with Mansonella perstans is often asymptomatic, but can cause a variety of symptoms including fever, skin rash, joint pain, and lymphadenopathy. Diagnosis is typically made by identifying microfilariae in a blood sample using a microscope.
Treatment and Prevention
Treatment for Mansonella perstans infection typically involves the use of antiparasitic drugs such as ivermectin or diethylcarbamazine. Prevention strategies include the use of insect repellent and protective clothing to reduce exposure to biting midges and blackflies.
Related Terms
External links
- Medical encyclopedia article on Mansonella perstans
- Wikipedia's article - Mansonella perstans
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