Methazolamide

From WikiMD
Jump to navigation Jump to search

Information about Methazolamide

Methazolamide and acetazolamide are carbonic anhydrase inhibitors used as diuretics and in the therapy of glaucoma.

Liver safety of Methazolamide

Both acetazolamide and methazolamide have been linked to rare cases of clinically apparent drug induced liver disease.

Mechanism of action of Methazolamide

Methazolamide (meth" a zol' a mide) and a++cetazolamide (a seet" a zol' a mide) and are inhibitors of carbonic anhydrase, an enzyme that converts carbon dioxide and water to carbonic acid. Inhibition of this enzyme in the kidney causes an alkalization of the urine and diuresis. In the eye, inhibition of carbonic anhydrase causes a decrease in intraocular pressure making these agents valuable in the treatment of glaucoma.

FDA approval information for Methazolamide

Methazolamide was approved for use in the United States in 1959 for the treatment of glaucoma. Methazolamide is available as tablets of 25 and 50 mg in generic forms and under the trade name Neptazane. Typical doses of methazolamide in adults with glaucoma are 50 to 100 mg two to three times daily.

Side effects of Methazolamide

The common side effects of acetazolamide and methazolamide are change in taste, numbness and tingling in fingers and toes, blurred vision, tinnitus, dizziness, decrease in hearing, polyuria, nausea, diarrhea, fatigue, and headache. Methazolamide and acetazolamide have similar chemical structures and are related to the sulfonamides and can cause allergic reactions including anaphylaxis, rash, erythema multiforme, and Stevens Johnson Syndrome.

List of diuretics

Carbonic Anhydrase Inhibitors

Loop Diuretics

Potassium-Sparing Diuretics

Thiazide Diuretics

Vasopressin Antagonists

Antihypertensive agents

Cost and Coupons - Methazolamide

Reviews for Methazolamide

This article is a stub. YOU can help Wikimd by expanding it!

Articles on Methazolamide

Wikipedia

Learn more about Methazolamide

Help WikiMD

Find something you can improve? Join WikiMD as an an editor and help improve this page or others.

Apple bitten.svg

WikiMD is a free medical encyclopedia and wellnesspedia moderated by medical professionals.

W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's insurance Weight loss program can HELP*

Quick links: Medicine Portal | Encyclopedia‏‎‏‎ | Gray's Anatomy‏‎ | Topics‏‎ |‏‎ Diseases‏‎ | Drugs | Wellness | Obesity‏‎ | Metabolic syndrome | Weight loss*
Disclaimer: The entire contents of WIKIMD.ORG are for informational purposes only and do not render medical advice or professional services. If you have a medical emergency, you should CALL 911 immediately! Given the nature of the wiki, the information provided may not be accurate, misleading and or incorrect. Use the information on this wiki at your own risk! See full Disclaimer.
Link to this page: <a href="http://www.wikimd.org/wiki/Methazolamide">Methazolamide</a>

  • Individual results may vary for weight loss from our sponsors.